| Date | Location | Result | |
| 03/01/22 | Conway, AR | Central Ark. 74, Stetson 73 | Box score |
| 02/26/22 | DeLand, FL | North Florida 74, Stetson 69 | Box score |
| 02/23/22 | Kennesaw, GA | Kennesaw St. 75, Stetson 71 | Box score |
| 02/19/22 | Lynchburg, VA | Liberty 88, Stetson 82 | Box score |
| 02/16/22 | DeLand, FL | Jacksonville 67, Stetson 45 | Box score |
| 02/12/22 | Fort Myers, FL | FGCU 89, Stetson 82 | Box score |
| 02/09/22 | DeLand, FL | Stetson 63, Jacksonville St. 57 | Box score |
| 02/05/22 | Conway, AR | Central Ark. 79, Stetson 75 | Box score |
| 02/03/22 | Nashville, TN | Stetson 77, Lipscomb 71 | Box score |
| 01/29/22 | DeLand, FL | Stetson 113, Eastern Ky. 95 | Box score |
| 01/27/22 | DeLand, FL | Bellarmine 72, Stetson 47 | Box score |
| 01/22/22 | Florence, AL | Stetson 67, North Ala. 65 | Box score |
| 01/18/22 | DeLand, FL | FGCU 93, Stetson 91 | Box score |
| 01/15/22 | DeLand, FL | Kennesaw St. 77, Stetson 49 | Box score |
| 01/11/22 | Jacksonville, FL | Jacksonville 57, Stetson 50 | Box score |
| 01/08/22 | Jacksonville, FL | Stetson 68, North Florida 66 | Box score |
| 01/04/22 | DeLand, FL | Liberty 75, Stetson 59 | Box score |
| 12/30/21 | DeLand, FL | Stetson 77, Point U. 65 | Box score |
| 12/22/21 | DeLand, FL | Stetson 97, Piedmont 53 | Box score |
| 12/20/21 | Coral Gables, FL | Miami (FL) 82, Stetson 72 | Box score |
| 12/16/21 | DeLand, FL | Stetson 67, Col. of Charleston 59 | Box score |
| 12/13/21 | DeLand, FL | Stetson 104, Johnson (FL) 58 | Box score |
| 12/11/21 | DeLand, FL | Ohio 55, Stetson 45 | Box score |
| 12/04/21 | Miami, FL | FIU 72, Stetson 65 | Box score |
| 12/01/21 | Boca Raton, FL | Fla. Atlantic 83, Stetson 73 | Box score |
| 11/27/21 | DeLand, FL | Campbell 60, Stetson 58 | Box score |
| 11/19/21 | Beaumont, TX | Stetson 60, Lamar University 59 | Box score |
| 11/17/21 | Oxford, OH | Miami (OH) 80, Stetson 65 | Box score |
| 11/12/21 | Atlanta, GA | Georgia Tech 77, Stetson 52 | Box score |
| 11/09/21 | DeLand, FL | Stetson 74, Fla. Memorial 67 | Box score |